The garcinia cambogia review starts with the garcinia cambogia extract known as HCA. According to Dr. Oz can help suppress your appetite and improve your mood; however, Dr. Oz's website has no citation or reference proving its effectiveness.
One study I reviewed acknowledged HCA as the active ingredient. It found no significant loss in weight in patients taking 1500mg of HCA for 12 weeks. A total of 135 subjects were used.
HCA is believed to possibly be safe when used properly for a period of 12 weeks or less. Currently, there is no long-term, reliable information about the use of garcinia. It is not recommended for pregnant and lactating women.
Another study reviewed occurred with women that were mildly overweight. They took their garcinia cambogia prior to meals for a total duration of 12 weeks. There was no report of decreased appetite but there was a decrease in weight seen.
One more study, a 2nd one with more moderately obese people, took HCA before meals and that study too also resulted in weight loss over a period of 8 weeks.
Adverse reactions seen with garcinia include nausea, GI discomfort and headache.
It is theorized that the garcinia fruit rind extract which contains 50% HCA interferes with fat generation known as lipogenesis. Some researchers believe that garcinia inhibits the supply of fatty acids without affecting fat conversion.
Preliminary research states or suggests that garcinia inhibits the accumulation of fat droplets in fat cells and thereby reduces fat levels and decreases fat accumulation in the liver; however, the true method of how garcinia works is not yet elucidated.
In addition, it is also theorized that HCA can improve exercise endurance by increasing the use of fat burning and decreasing carbohydrate use. In animal research studies, it has been suggested that HCA might suppress appetite.
Dr. Oz does state that garcinia increases serotonin levels. Antidepressants work by increasing serotonin levels; however, when garcinia is used along with antidepressants there is a risk of too much serotonin which is known as serotonin toxicity.
For these reasons, garcinia should not be used if you are taking an antidepressant.
Garcinia for weight loss, orally with an extract containing 50% HCA, 1000mg three times daily has been used for weight loss. HCA (50%), 500mg four times daily was also used for weight loss.
If you are going to try this, I highly suggest you take it before meals since that is how it was administered in those who lost weight. It seems that Arnold Schwarzenegger's Encyclopedia also recognizes the fact that Garcinia "inhibits fatty acid and cholesterol biosynthesis and has the ability to suppress appetite and reduce weight gain. It is used to prevent and control obesity." This is due to the hydroxycitrate within the fruit.
The garcinia on this webpage contains the same amount of HCA used in the clinical studies that showed effectiveness (See below). Thank you.
1. Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1956-600.
2. Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29.
3. Mattes Rd, Bormann L. Effects of (-)-hydroxycitric acid on appetitive variables. Physiol Behav 2000;71:87-94
4. Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180
5. Kovacs EM, Westerterp-Plantenga MS, Saris WH. The effects of 2-week ingestion of (-)-hydroxycitrate and (-)-hydroxcitrate combined with medium-chain triglycerides on satiety, fat oxidation, energy expenditure and body weight. Int J Obes Relat Metab Disord 2001;25:1087-94.